TEZSPIRE is an add-on maintenance treatment for people aged 12 and older with severe asthma or inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP). TEZSPIRE is not a rescue medicine.Video Icon

TEZSPIRE is an add-on maintenance treatment for people aged 12 and older with severe asthma or inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP). TEZSPIRE is not a rescue medicine.Video Icon  

Taking TEZSPIRE

One dose every four weeks. Whether you have severe asthma, nasal polyps, or both, TEZSPIRE offers convenient at-home and in-office options to help meet your needs.

You and your doctor decide which TEZSPIRE administration option works best for you

Straightforward dosing:

TEZSPIRE offers two administration options for flexibility and convenience:

TEZSPIRE Simple Dosage

Once every four weeks
with either administration option

 

TEZSPIRE offers two administration options for flexibility and convenience:

Taking TEZSPIRE Administration By Self

By self-administration
with the TEZSPIRE Pre-filled Pen, which can be convenient at home or on the go

Taking TEZSPIRE Administration By Doctor

At your doctor’s office
with a pre-filled syringe, if you and your doctor prefer in-office administration

TEZSPIRE is not a steroid or an inhaler. It’s an add-on treatment that does not replace your current asthma or nasal polyps medication(s).

Getting to know your TEZSPIRE Pre-filled Pen for self-administration

The TEZSPIRE Pre-filled Pen provides a convenient way to inject yourself without needing to visit your doctor for every dose. Your doctor should show you or your caregiver how it works and how to use it before your first injection.

Read the Instructions for Use
before you start using your TEZSPIRE Pre-filled Pen.
If you have further questions, please contact your doctor.

TEZSPIRE Pen For Self-Administration TEZSPIRE Pen For Self-Administration

Watch a demonstration on how to use the TEZSPIRE Pre-filled Pen

The video below is divided into chapters that demonstrate how to inject with the TEZSPIRE Pre-filled Pen. Watch the video in full or select a specific chapter from the list on the right.

Choose a chapter:

  • Introduction and Indication
  • Instructions for use
  • Materials needed for self-injection
  • Preparing your TEZSPIRE Pre-filled Pen for self-administration
  • How to inject
  • Disposing of the pre-filled pen
  • Important Safety Information

  

    • Introduction and Indication
    • Instructions for use
    • Materials needed for self-injection
    • Preparing your TEZSPIRE Pre-filled Pen for self-administration
    • How to inject
    • Disposing of the pre-filled pen
    • Important Safety Information

This demonstration video gives you basic information about the TEZSPIRE Pre-filled Pen. It is important that you thoroughly
review the Instructions for Use. These instructions cover everything you need to know about how to use TEZSPIRE. The information on this website does not replace the Instructions for Use.

TEZSPIRE Downloadable Guide

The TEZSPIRE self-injection journey guide

“My TEZSPIRE Injection Journey Resource for Self-Administration” provides helpful, step-by-step information on self-administration, resources and tools, specialty pharmacy information, frequently asked questions, and more.

Download now
TEZSPIRE Downloadable Guide

The TEZSPIRE Self-Injection Welcome Kit

The "TEZSPIRE Self-Injection Welcome Kit" provides resources to support you throughout your injection experience and help you get the most from your treatment.

Download now

Nurse Educators are available if needed to walk you through the injection.*

Nurse educators are available Monday-Friday, 8:00 AM-8:00 PM ET. Call 1-888-TZSPIRE
(1-888-897-7473).

*Nurse Educators are nurses by training, but they are not part of your treatment team or an extension of your doctor’s office. Nurse Educators do not inject patients with TEZSPIRE. You will be referred to your doctor’s office for clinical advice.

Stay connected with TEZSPIRE

We know how much your condition can impact your life and we want to help you have better control of it. Sign up for the TEZSPIRE newsletter for helpful tools that can support you on your journey. You’ll get:

  • Inspiration Icon

    Informative articles about living with your condition

     

  • Mobile Tools Icon

    Valuable resources to help you along the way

     

  • Spotify Icon

    A soothing Spotify® playlist

Important Safety Information

+

Important Safety Information

Do not use TEZSPIRE if you are allergic to tezepelumab-ekko or any of its ingredients.

Do not use to treat sudden breathing problems.

TEZSPIRE may cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after your TEZSPIRE injection. Allergic reactions can sometimes happen hours or days after you get a dose of TEZSPIRE. Call your healthcare provider or get emergency help right away if you get any of the following symptoms of an allergic reaction:
    • rash
    • breathing problems
    • hives
    • red, itchy, swollen, or inflamed eyes
    • swelling of your face, mouth, and tongue
    • fainting, dizziness, feeling lightheaded

Before using TEZSPIRE, tell your healthcare provider about all of your medical conditions, including if you:

  • have ever had a severe allergic reaction.
  • have a parasitic (helminth) infection.
  • have recently received or are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with TEZSPIRE.
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if TEZSPIRE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use TEZSPIRE.
  • are taking prescription and over-the-counter medicines, vitamins, or herbal supplements.

Do not change or stop taking your other asthma medicines unless instructed to do so by your healthcare provider.

The most common side effects of TEZSPIRE include: Sore throat, joint and back pain, common cold symptoms, flu, upper respiratory tract infections, injection site reactions, and nose bleeds. These are not all the possible side effects.

Approved Use

TEZSPIRE is a prescription medicine used:

  • with other asthma medicines for the maintenance treatment of severe asthma in people 12 years of age and older whose asthma is not controlled with their current asthma medicine.
  • with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in people 12 years of age and older whose CRSwNP is not controlled with their current CRSwNP medicine.

TEZSPIRE helps:

  • prevent severe asthma attacks (exacerbations) and can improve your breathing.
  • reduce the size of your polyps, improve symptoms including i.e. nasal congestion and loss of smell, and reduce the need for oral corticosteroids and surgery for your nasal polyps in CRSwNP.

TEZSPIRE is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with TEZSPIRE.

Full Prescribing Information including Patient Information and Instructions for Use.

You may report side effects related to AstraZeneca products Opens new window.