Understanding Medicare Options
Get more details about Medicare from the official US government handbook
Download nowThe TEZSPIRE Together Co-pay Program* may help eligible commercially insured patients reduce out-of-pocket costs.
If you have Medicare, Medicare Advantage, or no insurance, there may still be support options available.† TEZSPIRE Together is here to help. Contact us at 1-888-TZSPIRE (1-888-897-7473).
*For eligible commercially insured patients only. Eligibility criteria and program maximums apply. Please click to see the full Terms and Conditions.
†Program eligibility is based on the nonprofit’s criteria. TEZSPIRE Together has no control over these programs and provides referrals as a courtesy only.
Heads up! If you miss the call from the specialty pharmacy, your delivery might be delayed. They can’t ship your medication until they speak with you.
Once you’ve confirmed shipping details with the specialty pharmacy, TEZSPIRE will be shipped right to you.
Open the package and place the medication in the refrigerator until you're ready to inject.
Because TEZSPIRE requires refrigeration, it’s handled a little differently. It will be prepared by a specialty pharmacy, not your typical pharmacy. The specialty pharmacy works with your health insurance representative and contacts you directly to coordinate shipping and payment details.
The TEZSPIRE Together Co-pay Program* may help eligible commercially insured patients reduce out-of-pocket costs.
If you have Medicare, Medicare Advantage, or no insurance, there may still be support options available.† TEZSPIRE Together is here to help. Contact us at 1-888-TZSPIRE (1-888-897-7473).
*For eligible commercially insured patients only. Eligibility criteria and program maximums apply. Please click to see the full Terms and Conditions.
†Program eligibility is based on the nonprofit’s criteria. TEZSPIRE Together has no control over these programs and provides referrals as a courtesy only.
Heads up! If you miss the call from the specialty pharmacy, your delivery might be delayed. They can’t ship your medication until they speak with you.
Once you’ve confirmed shipping details with the specialty pharmacy, your TEZSPIRE will be shipped right to you.
Open the package and place the medication in the refrigerator until you're ready to inject.
If your doctor prescribes the TEZSPIRE® Pre-filled Syringe to be administered in their office, there's no need to pick it up at a pharmacy. Instead, it will be shipped directly to your provider.
The office will contact you to schedule your first injection appointment.
Before your appointment, give your doctor’s office a quick call to confirm the medication has arrived and is ready. It’s a quick step that helps keep things on track.
Once you arrive at your appointment, your doctor will administer your first dose. From there, you’ll continue treatment one appointment and one injection at a time.
The TEZSPIRE Together Co-Pay Program* may help eligible commercially insured patients reduce out-of-pocket costs.
Verify with your provider that you have enrolled in the co-pay program.
*For eligible commercially insured patients only. Eligibility criteria and program maximums apply. See TEZSPIRE.com for full Terms and Conditions.
†Patients who are residents of Massachusetts or Rhode Island are not eligible for injection administration support.
If you have Medicare, Medicare Advantage, or no insurance, there may still be support options available.‡ TEZSPIRE Together is here to help. Contact us at 1-888-TZSPIRE (1-888-897-7473).
‡Program eligibility is based on the nonprofit’s criteria. TEZSPIRE Together has no control over these programs and provides referrals as a courtesy only.
If your doctor prescribes the TEZSPIRE® Pre-filled Syringe to be administered in their office, there's no need to pick it up at a pharmacy. Instead, it will be shipped directly to your provider.
The office will contact you to schedule your first injection appointment.
Before your appointment, give your doctor’s office a quick call to confirm the medication has arrived and is ready. It’s a quick step that helps keep things on track.
Once you arrive at your appointment, your doctor will administer your first dose. From there, you’ll continue treatment one appointment and one injection at a time.
Specialty pharmacies are different from your typical pharmacy. They focus on medications that require special handling or expertise. They also help with all the behind-the-scenes steps, like confirming health insurance coverage and setting up the delivery of medications.
See what resources may be available to help with the cost of treatment.

Enroll in the TEZSPIRE Together Co-pay Program
For other insurance types:
You’re not alone on your treatment journey. TEZSPIRE Together offers tools, guidance, and real-time support right from the start.

Our nurse educators are trained to help you by answering questions you have about your TEZSPIRE medication, treatment, and navigation. They provide supplemental injection support and additional resources to help you on your TEZSPIRE journey. Call 1-888-TEZSPIRE (1-888-897-7473) Monday-Friday, 8:00AM-8:00PM ET.
*TEZSPIRE Together Nurse Educators are nurses by training and are only available to patients prescribed TEZSPIRE. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. They do not inject patients with TEZSPIRE. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.
Explore tips and tools to help you self-inject.
The information on this website does not replace the Instructions for Use.
For supplemental injection support call 1-800-772-6436.


People on Medicare who need help paying for their prescriptions may be eligible to receive a low-income subsidy (also known as Extra Help).
You can apply for Medicare Extra Help by completing the Social Security Application for Medicare Extra Help with Medicare Prescription Drug Plan Costs (Form SSA-1020). There are multiple ways to complete this form, based on your preference. You can:
Apply online at https://www.socialsecurity.gov/extrahelp
Apply on the phone or request an application by calling the Social Security Administration at 1-800-722-1213
Apply at your local Social Security office

Get more details about Medicare from the official US government handbook
Download nowTo find out if you qualify for Medicaid, or for more information about copayments in your state, please visit: https://www.medicaid.gov/state-overviews
Medicare Extra Help determinations are made by Medicare and the US government. TEZSPIRE Together does not determine eligibility for Medicare Extra Help nor have any impact or influence on Medicare’s determinations.
Medicare Advantage: Affordability gaps will be assessed for patients with an out-of-pocket cost greater than $100.
TEZSPIRE Together can refer you to independent, nonprofit patient assistance programs that may be able to help you afford your out-of-pocket costs for TEZSPIRE.

The TEZSPIRE Together Patient Assistance Program (PAP) is a nonprofit program sponsored by Amgen. It was designed to assist patients who have a financial need and are uninsured or underinsured.
If you would like to see if you are eligible, call 1-888-TZSPIRE (1-888-897-7473), 8:00AM-8:00PM ET, Monday–Friday.
There may also be third-party foundation support available. Third-party foundation support is provided through independent charitable patient assistance programs and not through TEZSPIRE Together. Program eligibility is determined by the charity’s criteria. TEZSPIRE Together has no control over independent third-party programs. For more information on third-party support, call 1-888-TZSPIRE (1-888-897-7473), 8:00AM-8:00PM ET, Monday–Friday.
Because TEZSPIRE requires special handling and refrigeration, it is usually filled through a specialty pharmacy. That pharmacy will work with your doctor’s office, your insurance company, and you to make sure the medication is shipped safely and on time.
The specialty pharmacy needs to speak with you to confirm important details before they can ship your medication. This includes your insurance information, delivery address, payment details, and co-pay information (if applicable). It’s a required step to make sure everything is accurate and that your TEZSPIRE gets to the right place on time.
If they can't reach you, your medication may be delayed. Specialty pharmacies usually call from an 800 or 888 number, so be on the lookout.
To enroll, please go to TEZSPIRE Together and click on the “Enroll Now” button. You can also enroll over the phone. Please call TEZSPIRE Together at 1-800-818-1770.
You must be commercially insured, and your health plan must provide coverage for your TEZSPIRE prescription. You must agree to the TEZSPIRE Together Co-pay Program Terms and Conditions, be a resident of the United States or its territories, and agree to the Patient Authorization and all applicable patient consents. You must continue to meet the Program’s eligibility requirements to keep receiving program benefits. You can click to see the full Terms and Conditions of the TEZSPIRE Together Co-pay Program.*
*Eligibility criteria and program maximums apply.
The TEZSPIRE Together Patient Support Program is designed to help you manage your journey right from the start. TEZSPIRE Together offers:
*TEZSPIRE Together Nurse Educators are not part of your treatment team and do not provide medical advice, nursing, or case management services. TEZSPIRE Together Nurse Educators will not inject patients with TEZSPIRE. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.
Give your doctor’s office a call before your injection appointment to confirm they received your medication and have it ready for you. When you arrive, your provider will administer your first treatment dose. From there, you’ll receive TEZSPIRE one appointment and one injection at a time.
Watch the demonstration video for a brief introduction on using the TEZSPIRE Pre-filled Pen. It’s important to also review the Instructions for Use, which cover everything you will need to know about self-injecting.
The timing can vary, but many patients may get their first dose within a few weeks after their prescription is submitted. Before your injection can happen, a few steps need to be completed, like verifying insurance, checking eligibility for savings programs, and (if needed) coordinating delivery through a specialty pharmacy.
If it’s about your health, symptoms, or how TEZSPIRE is working for you, your doctor or care team is the best place to start. If you are experiencing any side effects, please call your healthcare provider or the manufacturer’s medical information line at 1-800-236-9933.
For supplemental injection support call 1-800-772-6436.
It is important that every patient read and understand the full TEZSPIRE® Co-Pay Card Terms and Conditions. The following summary is not a substitute for reviewing the Terms and Conditions in their entirety.
As further described below, in general:
I. ELIGIBILITY
*Eligibility Criteria: Subject to program limitations and terms and conditions, the TEZSPIRE® Co-Pay Card is open to patients who have been prescribed TEZSPIRE and who have commercial or private insurance that covers TEZSPIRE, including state and federal plans commonly referred to as “healthcare exchange plans.” This program helps eligible patients cover TEZSPIRE out-of-pocket medication and in-office administration costs, up to program limits. Patients who are residents of Massachusetts or Rhode Island are not eligible for injection administration support. The Co-Pay Card does not cover any other costs related to office visits. There is no income requirement to participate in this program.
This offer is not valid for patients whose TEZSPIRE prescription is paid for in whole or in part by Medicare, Medicaid, or any other federal or state healthcare program. The TEZSPIRE Co-Pay Card cannot be combined with any other savings, free trial, free goods or similar offer related to TEZSPIRE. It is not valid for cash-paying patients or where prohibited by law. A patient is considered cash-paying where the patient has no insurance coverage for TEZSPIRE or where the patient has commercial or private insurance but Amgen and AstraZeneca in their sole discretion determine the patient is effectively uninsured because such coverage does not provide a material level of financial assistance for the cost of a TEZSPIRE prescription. This offer is only valid in the United States, Puerto Rico, and the US territories.
II. PROGRAM BENEFITS
The TEZSPIRE Co-Pay Card may modify the benefit amount, unilaterally determined by Amgen and AstraZeneca in their sole discretion, to satisfy the out-of-pocket cost sharing requirement for any patient whose plan or plan agent (including, but not limited to, a Pharmacy Benefit Manager (PBM)) requires enrollment in the TEZSPIRE Co-Pay Card as a condition of the plan or PBM waiving some or all of an otherwise applicable patient out-of-pocket cost sharing amount. These programs are often referred to as co-pay maximizer programs. If you believe your commercial insurance plan may have such limitations, please contact TEZSPIRE Together Co-pay Program at 1-800-818-1770. Health plans and Pharmacy Benefit Managers are prohibited from enrolling or assisting in the enrollment of patients in the TEZSPIRE Co-Pay Card. The patient, or his/her legal representative, must personally enroll in the TEZSPIRE Co-Pay Card in order to be eligible for program benefits.
If at any time a patient begins receiving coverage for medications or in-office administration costs under any federal, state, or government healthcare program (including but not limited to Medicare, Medicaid, TRICARE, Department of Defense, or Veteran Affairs programs), the patient will no longer be able to use this card and must contact the TEZSPIRE Together Co Pay Program at 1-800-818-1770 (Monday through Friday, from 9AM to 8PM EST) to stop your participation in this program.
Patients may not seek reimbursement for the value received from the TEZSPIRE Co-Pay Card from any third-party payers, including a flexible spending account or healthcare savings account. Participating in this program means that you are ensuring you comply with any required disclosure regarding your participation in the TEZSPIRE Co-Pay Card of your insurance carrier or pharmacy benefit manager. Restrictions may apply. Offer subject to change or discontinuation without notice. This is not health insurance.
iii. PROGRAM DETAILS
For all eligible patients the TEZSPIRE® Co-Pay Card offers:
Program coverage through the TEZSPIRE Co-Pay Card is contingent on (1) the submission of the required Explanation of Benefits (EOB) form within 180 days of the date of approval documented on the EOB for medical benefit claims or (2) the submission of the claim within 180 days of the date of service for pharmacy benefit claims.
Maximum Program Benefit, Patient Total Program Benefit, Benefits May Change, End or Vary Without Notice: The program provides up to a Maximum Program Benefit of support to reduce a patient’s out-of-pocket costs that Amgen and AstraZeneca will provide per patient for each calendar year, which must be applied to the TEZSPIRE® patient’s out-of-pocket costs (co-pay, deductible, or co-insurance and annual out-of-pocket maximum). Patient Total Program Benefit amounts are unilaterally determined by Amgen and AstraZeneca in their sole discretion and will not exceed the Maximum Program Benefit. The Patient Total Program Benefit may be less than the Maximum Program Benefit, depending on the terms of a patient’s plan, and may vary among individual patients covered by different plans, based on factors determined solely by Amgen and AstraZeneca, to ensure all program funds are used for the benefit of the patient. Each patient is responsible for costs above the Patient Total Program Benefit amounts. Please ask your TEZSPIRE Together Co pay Program Representative to help you understand whether your particular insurance coverage is likely to result in your reaching the Maximum Program Benefit or your Patient Total Program Benefit amount by calling 1-800-818-1770. Participating patients are solely responsible for updating Amgen and AstraZeneca with changes to their insurance including, but not limited to, initiation of insurance provided by the government, the addition of any coverage terms that do not apply TEZSPIRE Co-Pay Card benefits to reduce a patient’s out-of-pocket costs, such as accumulator adjustment benefit design or a co-pay maximization program. Participating patients are responsible for providing Amgen and AstraZeneca with accurate information necessary to determine program eligibility. By accepting payments from Amgen and AstraZeneca made on behalf of participating patients, participating PBMs and Plans likewise are responsible for providing Amgen and AstraZeneca with accurate information regarding patient eligibility.
Patients may use the card every time they receive a prescription fill or dose of TEZSPIRE, up to the Maximum Program Benefit or Patient Total Program Benefit. Benefits reset each calendar year. Re-enrollment in the program is required at regular intervals. Patients may continue in the program as long as patient re-enrolls as required by Amgen and AstraZeneca and continues to meet all of the program’s eligibility requirements during participation in the program. Patients can enroll/re-enroll by going to copay.TEZSPIRETogether.com or by calling 1-800-818-1770.
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Do not use TEZSPIRE if you are allergic to tezepelumab-ekko or any of its ingredients.
Do not use to treat sudden breathing problems.
TEZSPIRE may cause serious side effects, including:
Before using TEZSPIRE, tell your healthcare provider about all of your medical conditions, including if you:
Do not change or stop taking your other asthma medicines unless instructed to do so by your healthcare provider.
The most common side effects of TEZSPIRE include: Sore throat, joint and back pain, common cold symptoms, flu, upper respiratory tract infections, injection site reactions, and nose bleeds. These are not all the possible side effects.
Approved Use
TEZSPIRE is a prescription medicine used:
TEZSPIRE helps:
TEZSPIRE is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with TEZSPIRE.
Full Prescribing Information,
including Patient Information and Instructions for Use.
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